Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease - Characteristics and treatment
Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease - Characteristics and treatment
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DOI：
10.1016/s0733-8619(05)70228-0
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发表时间：
2000-11-01
影响因子：
2.4
通讯作者：
Cummings, JL
中科院分区：
文献类型：
--
作者：
Chung, JA;Cummings, JL
神经精神症状在阿尔茨海默病中很常见。人格改变、情绪障碍和精神病是常见的，并可能在同一个病人中共存。神经精神症状可能是疾病发作的信号，并且经常波动和复发。这些症状与更快的认知和功能下降有关，可能导致机构化。胆碱能治疗、疾病缓解治疗和精神药物可以改善这些症状。
Neuropsychiatric symptoms are common in Alzheimer's disease. Personality changes, mood disturbance, and psychosis are frequently seen and may coexist in the same patient. Neuropsychiatric symptoms may signal the onset of disease and often fluctuate and recur. These symptoms are associated with a more rapid cognitive and functional decline that can lead to institutionalization. Cholinergic therapy, disease-modifying therapy, and psychotropic medications can improve these symptoms.