Hurler's Syndrome: Deficiency of a Specific Beta Galactosidase Isoenzyme
Hurler's Syndrome: Deficiency of a Specific Beta Galactosidase Isoenzyme
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Hurler 综合征：特定 β 半乳糖苷酶同工酶缺乏
DOI：
10.1126/science.165.3893.611
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发表时间：
1969
期刊：
影响因子：
56.9
通讯作者：
J. O'Brien
中科院分区：
文献类型：
--
作者：
M. Ho;J. O'Brien
在5例Hurler综合征（1 ~ 3型）患者的肝、肾组织中发现一种特异性不耐热β-半乳糖苷酶同工酶（最适pH 3 ~ 5）明显缺乏。
A marked deficiency of a specific thermolabile β-galactosidase isoenzyme (pH optimum 3 to 5) was found in liver and kidney tissues of five patients with the Hurler's syndrome (types 1 to 3).