B(0) magnetic field homogeneity and shimming for in vivo magnetic resonance spectroscopy.

B(0) magnetic field homogeneity and shimming for in vivo magnetic resonance spectroscopy.
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DOI:
10.1016/j.ab.2016.06.003
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发表时间:
2017-07-15
影响因子:
2.9
通讯作者:
de Graaf RA
de Graaf RA
中科院分区:
生物学4区
文献类型:
--
作者:
Juchem C;de Graaf RA

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B0条件的均匀化对于每个MR波谱(MRS)研究都是必要的。它的直接后果是窄谱线,可靠的分离和量化的生化物质,从而实验上可获得的代谢信息基本上依赖。除了谱线宽度之外,不希望的B0不均匀性还损害MRS实验的其他方面,例如依赖于精确频率定义的水抑制或编辑效率。因此,实验B0均匀化,称为B0匀场,是强制性的有意义的MRS,和高水平的B0匀场可以说是成功的MRS调查的最重要的成分之一。在这篇综述中,我们描述了在体MRS的B0均匀性的相关性,并总结了其实验优化的常见概念和具体解决方案。
The homogenization of B0 conditions is necessary for every MR spectroscopy (MRS) investigation. Its direct consequence is narrow spectral lines, on which reliable separation and quantification of biochemicals, and thus experimentally obtainable metabolic information fundamentally relies. Besides spectral linewidth, unwanted B0 inhomogeneity also impairs other aspects of the MRS experiment, such as water suppression or editing efficiency, that rely on exact frequency definition. Experimental B0 homogenization, called B0 shimming, is therefore mandatory for meaningful MRS, and high-level B0 shimming is arguably one of the most important ingredients for successful MRS investigations. In this review, we describe the relevance of B0 homogeneity for in vivo MRS and summarize common concepts and specific solutions for its experimental optimization.
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