Chemoenzymatic synthesis of tumor-associated antigen N3 minor octasaccharide
Chemoenzymatic synthesis of tumor-associated antigen N3 minor octasaccharide
复制标题
肿瘤相关抗原N3小八糖的化学酶法合成
DOI:
10.1080/07328303.2017.1315123
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发表时间:
2016
影响因子:
1
通讯作者:
Cao Hongzhi
中科院分区:
文献类型:
--
作者:
Han Zhipeng;Chen Congcong;Meng Caicai;Gao Tian;Peng Peng;Chen Xi;Wang Fengshan;Cao Hongzhi
GRAPHICAL ABSTRACT ABSTRACT A highly efficient chemoenzymatic approach was developed for the preparative scale synthesis of complex tumor-associated antigen N3 minor octasaccharide. The success of this approach relies on the highly efficient one-pot multi-enzyme based sequential enzymatic elongation of a chemically synthesized branched tetrasaccharide core structure.