Functional differentiation of endosomes in Arabidopsis cells
Functional differentiation of endosomes in Arabidopsis cells
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DOI：
10.1111/j.1365-313x.2004.02249.x
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发表时间：
2004-12-01
期刊：
影响因子：
7.2
通讯作者：
Nakano, A
中科院分区：
文献类型：
--
作者：
Ueda, T;Uemura, T;Nakano, A
内吞作用在植物生理学中起着重要作用，但内吞细胞器是如何组织的还不清楚。我们提出的证据表明，内体功能分化拟南芥细胞。两种类型的Rab 5相关的GTP酶定位在不同的人口的内体在一个部分重叠的方式。Ara 7和Rha 1与AtVamp 727一起位于早期类型的内体上，在那里发生质膜蛋白的再循环。与此相反，植物特有的Rab 5，Ara 6，居住在不同的内体与prevacuolar SNARE。Ara 6和Ara 7/Rha 1的相互梯度部分重叠的定位表明内体从一个成熟到另一个。
Endocytosis plays an important role in plant physiology, but how endocytic organelles are organized remains unknown. We present the evidence that endosomes are functionally differentiated in Arabidopsis cells. Two types of Rab5-related GTPases are localized on distinct population of endosomes in a partially overlapping manner. Ara7 and Rha1 are on an early type of endosomes with AtVamp727, where recycling of plasma membrane proteins occurs. In contrast, the plant-unique Rab5, Ara6, resides on distinct endosomes with the prevacuolar SNAREs. Partially overlapping localization of Ara6 and Ara7/Rha1 with reciprocal gradients suggests maturation of endosomes from one to the other.