Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study
Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study
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DOI：
10.1111/ggi.13508
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发表时间：
2018-10-01
影响因子：
3.3
通讯作者：
Maeda, Yoshinobu
中科院分区：
文献类型：
--
作者：
Hatta, Kodai;Ikebe, Kazunori;Maeda, Yoshinobu
目的：以前的研究已经报道了牙齿脱落或牙周状况与认知功能之间的显着关联;然而，动物实验研究表明，咬合可能是认知能力下降的一个更重要的因素。本研究的目的是调查的影响，缺乏后咬合支持的剩余牙齿的认知功能下降超过3年的时间在80岁的日本people.Methods：参与者是社区居住的老年人（n=515，年龄79-81岁）。认知功能采用日本版的蒙特利尔认知评估进行测量。在基线时，参与者被分为两组：有和没有后咬合支持。在3年的时间里，日本版蒙特利尔认知评估评分下降≥ 3分的参与者被定义为下降组。Logistic回归分析进行了下降，在日本版的蒙特利尔认知评估分数，包括牙齿状态和可能的危险因素作为individuals.Results：更多的参与者没有后咬合支持倾向于在认知下降组（49.4%）比在维持组（38.5%;卡方检验，P=0.02）。Logistic回归分析显示，即使调整了其他危险因素，缺乏后牙咬合支持也是认知能力下降的一个重要变量（比值比1.55，P=0.03）。然而，牙齿的数量或平均牙周袋深度与认知decline.Conclusions：目前的研究结果表明，缺乏后咬合支持预测认知能力下降的发病率，即使在调整可能的危险因素，在社区居住的老年人。
Aim: Previous studies have reported significant associations between tooth loss or periodontal status and cognitive function; however, animal experimental studies have shown that occlusion might be a more important factor in cognitive decline. The purpose of the present study was to investigate the influence of a lack of posterior occlusal support by residual teeth on the decline of cognitive function over a 3-year period among 80-year-old Japanese people.Methods: Participants were community-dwelling older adults (n=515, age 79-81 years). Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment. At baseline, participants were divided into two groups: those with and without posterior occlusal support. Participants whose Japanese version of the Montreal Cognitive Assessment score decreased by >= 3 points over the 3-year period were defined as the declined group. Logistic regression was carried out for the decline in Japanese version of the Montreal Cognitive Assessment scores, including dental status and possible risk factors as independent variables.Results: More participants without posterior occlusal support tended to be in the cognitive decline group (49.4%) than in the maintained group (38.5%; chi(2)-test, P=0.02). Logistic regression analysis showed that a lack of posterior occlusal support was a significant variable (odds ratio 1.55, P=0.03) for cognitive decline, even after adjusting for other risk factors. However, the number of teeth or mean periodontal pocket depth was not significantly correlated with cognitive decline.Conclusions: The present findings suggest that a lack of posterior occlusal support predicted the incidence of cognitive decline, even after adjusting for possible risk factors in community-dwelling old-old people.