Successful treatment of primary aldosteronism due to computed tomography-negative microadenoma
Successful treatment of primary aldosteronism due to computed tomography-negative microadenoma
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DOI：
10.1046/j.1442-2042.2003.00674.x
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发表时间：
2003-10-01
影响因子：
2.6
通讯作者：
Nakao, K
中科院分区：
文献类型：
--
作者：
Nishizawa, K;Nakamura, E;Nakao, K
我们报告一例醛固酮微腺瘤被正确诊断，因此通过腹腔镜肾上腺切除术进行微创治疗。一位58岁的女性，表现为心悸和肌肉无力。她表现出高血压、低钾血症和醛固酮排泄增加伴肾素活性抑制。因此，建议为原发性醛固酮增多症。虽然肾上腺的肾上腺血管造影和计算机断层扫描结果正常，但肾上腺静脉取样试验表明右肾上腺醛固酮过量。我们诊断为右肾上腺产生醛固酮的微腺瘤，并进行了肾上腺切除术。病人术后血压正常，组织病理学检查显示一个直径5 mm的微腺瘤。
We report a case of aldosterone-producing microadenoma that was correctly diagnosed and thus treated less invasively by laparoscopic adrenalectomy. A 58-year-old woman presented with palpitation and muscular weakness. She exhibited hypertension, hypokalemia and increased aldosterone excretion with suppressed renin activity. Therefore, primary aldosteronism was suggested. Although adrenal scintigram and computed tomography findings in the adrenal glands were normal, adrenal venous sampling tests indicated an overproduction of aldosterone in the right adrenal gland. We diagnosed an aldosterone-producing microadenoma in the right adrenal gland and performed an adrenalectomy. The patient became normotensive postoperatively and histopathological examination demonstrated a microadenoma, 5 mm in diameter.