Ubiquitination: RING for destruction?
Ubiquitination: RING for destruction?
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DOI:
10.1016/s0960-9822(00)00287-6
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发表时间:
2000-01-27
期刊:
影响因子:
9.2
通讯作者:
Freemont, PS
中科院分区:
文献类型:
--
作者:
Freemont, PS
Ubiquitination targets proteins for degradation and is a potent regulator of cellular protein function. Recent results implicate the RING finger domain in specific ubiquitination events; it is possible that all RING proteins act as E3 ubiquitin protein ligases, with implications for a variety of biological areas.