FORMOSE REACTIONS .4. SELECTIVE FORMATION OF TRIOSE FROM FORMALDEHYDE CATALYZED BY THIAZOLIUM SALT
FORMOSE REACTIONS .4. SELECTIVE FORMATION OF TRIOSE FROM FORMALDEHYDE CATALYZED BY THIAZOLIUM SALT
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DOI：
10.1021/ja00329a031
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发表时间：
1984-01-01
影响因子：
15
通讯作者：
INOUE, S
中科院分区：
文献类型：
--
作者：
MATSUMOTO, T;YAMAMOTO, H;INOUE, S
在噻唑盐催化的甲醛自缩合反应中，选择性地生成了二羟基丙酮(三糖)，而不是乙醇醛，并且产率很高。这是一种从该C1化合物合成三糖的简便而新颖的方法，具有很大的意义。描述了一个可以解释二羟基丙酮选择性形成的机理。
In the self-condensation of formaldehyde catalyzed by thiazolium salts, dihydroxyacetone (triose), but not glycolaldehyde, was formed selectively and in high yield. This is of much interest as a facile and novel synthesis of triose from this C1 compound. A mechanism which can account for the selective formation of dihydroxyacetone is described.