Hydrothermal preparation of tailored hydroxyapatite
Hydrothermal preparation of tailored hydroxyapatite
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DOI：
10.1007/s10853-006-7338-5
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发表时间：
2006-03-01
影响因子：
4.5
通讯作者：
Goto, S
中科院分区：
文献类型：
--
作者：
Ioku, K;Kawachi, G;Goto, S
采用水热蒸汽法制备陶瓷生物材料。羟磷灰石(Ca-10 (PO4)(6)(哦)(2);具有随机晶体表面的羟基磷灰石（HA）陶瓷已被用作骨修复材料，可以直接与天然骨结合。如果透明质酸材料可以具有定制的特定晶体表面，那么与烧结的透明质酸相比，它们应该具有吸附活性和骨导电性的优势。本研究在200℃以下的温度下，采用水热蒸汽暴露法制备了厚度约为50 μ m ~ 1mm的透明质酸多孔片材和尺寸约为50 μ m ~ 1mm的透明质酸多孔颗粒，并对其晶体表面进行了定制。具有可控晶体表面的透明质酸多孔片材和多孔颗粒适用于骨培养支架、骨移植材料和药物传递系统（DDS）。(c) 2006 b施普林格科学+商业传媒有限公司
Hydrothermal vapor treatment method was applied for preparation of ceramic biomaterials. Hydroxyapatite (Ca-10(PO4)(6)(OH)(2); HA) ceramics prepared by sintering with random crystal surface have already been used as bone-repairing materials which can directly bond to natural bones. If materials of HA could have the tailored specific crystal surface, they should have the advantage of adsorptive activity and osteoconductivity in comparison with the sintered HA. In the present study, porous HA sheets of about 50 mu m to 1 mm in thickness and porous HA granules of about 50 mu m to 1 mm in size with tailored crystal surface were prepared by the hydrothermal vapor exposure method at temperatures below 200 degrees C. Porous sheets and porous granules of HA with controlled crystal surface should be suitable for scaffold of cultured bone, for bone graft material and for drug delivery system (DDS). (c) 2006 Springer Science + Business Media, Inc.