Cardiac Autonomic Neuropathy and Early Progressive Renal Decline in Patients with Nonmacroalbuminuric Type 1 Diabetes
Cardiac Autonomic Neuropathy and Early Progressive Renal Decline in Patients with Nonmacroalbuminuric Type 1 Diabetes
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DOI：
10.2215/cjn.11441114
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发表时间：
2015-07-01
影响因子：
9.8
通讯作者：
Perkins, Bruce A.
中科院分区：
文献类型：
--
作者：
Orlov, Steven;Cherney, David Z. I.;Perkins, Bruce A.
背景和目的心脏自主神经病变可预测普通人群未来的不良肾脏结局。设计、设置、参与者和测量来自第一Joslin肾脏研究的具有正常白蛋白尿（n=204）或微量白蛋白尿（n=166）的参与者的子集在1991年1月至1992年4月进行的基线访问期间使用心率变异性进行心脏自主神经病变的评估。心脏自主神经病变定义为R-R变异（平均圆形结果）
Background and objectives Cardiac autonomic neuropathy predicts future adverse renal outcomes in the general population. This study sought to determine its relationship withearly progressive renal decline in type 1 diabetes.Design, setting, participants, & measurements A subset of participants with normoalbuminutia (n=204) or microalbumimuia (n=166) from the First Joslin Kidney Study underwent assessment for cardiac autonomic neuropathy using heart rate variability during baseline visits performed from January 1991 to April1992. Cardiac autonomic neuropathy was defined as an R-R variation (mean circular resultant)