Segmentation of the Aortic Valve Apparatus in 3D Echocardiographic Images: Deformable Modeling of a Branching Medial Structure.
Segmentation of the Aortic Valve Apparatus in 3D Echocardiographic Images: Deformable Modeling of a Branching Medial Structure.
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DOI：
10.1007/978-3-319-14678-2_20
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Yushkevich PA
中科院分区：
文献类型：
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作者：
Pouch AM;Tian S;Takabe M;Wang H;Yuan J;Cheung AT;Jackson BM;Gorman JH 3rd;Gorman RC;Yushkevich PA
三维超声心动图(3DE)是评估主动脉瓣装置复杂几何形状的有用工具。在3DE图像中分割这种结构是一项具有挑战性的任务，这得益于形状制导的可变形建模方法，该方法能够进行对象间的统计形状比较。先前的工作证明了使用连续内侧表示(cm-rep)作为瓣叶形状描述符的有效性。然而，它在整个主动脉瓣膜装置中的应用是有限的，因为该结构具有分支的内侧几何结构，不能在原始的cm-rep框架中明确地参数化。在这项工作中，我们展示了使用一种新的分支内侧建模范例可以准确地分割主动脉瓣膜装置。与人工分割相比，该分割方法在11个正常开放的主动脉瓣3DE图像上获得了0.6±0.1 mm(约1个体素)的平均边界位移。本研究为主动脉瓣形态的3DE定量分析提供了一种很有前景的方法。
3D echocardiographic (3DE) imaging is a useful tool for assessing the complex geometry of the aortic valve apparatus. Segmentation of this structure in 3DE images is a challenging task that benefits from shape-guided deformable modeling methods, which enable inter-subject statistical shape comparison. Prior work demonstrates the efficacy of using continuous medial representation (cm-rep) as a shape descriptor for valve leaflets. However, its application to the entire aortic valve apparatus is limited since the structure has a branching medial geometry that cannot be explicitly parameterized in the original cm-rep framework. In this work, we show that the aortic valve apparatus can be accurately segmented using a new branching medial modeling paradigm. The segmentation method achieves a mean boundary displacement of 0.6 ± 0.1 mm (approximately one voxel) relative to manual segmentation on 11 3DE images of normal open aortic valves. This study demonstrates a promising approach for quantitative 3DE analysis of aortic valve morphology.