Different spectral components of 24 h heart rate variability are related to different modes of death in chronic heart failure
Different spectral components of 24 h heart rate variability are related to different modes of death in chronic heart failure
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DOI：
10.1093/eurheartj/ehi067
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发表时间：
2005-02-01
影响因子：
39.3
通讯作者：
Malliani, A
中科院分区：
文献类型：
--
作者：
Guzzetti, S;La Rovere, MT;Malliani, A
目的评估是否从24小时Hotter记录的心率变异性（HRV）的分析提供了有关的死亡模式（泵衰竭与猝死）在慢性心力衰竭（CHF）的信息hereuratevariability（CHF）。方法和结果我们分析了24小时HRV在330个连续的CHF患者窦性心律。对24 h自动心率变异性的时域、谱域和分形分析指标进行了评价。分析临床评估、超声心动图、右心导管检查、运动试验、血液生化检查和心律失常类型的数据。随访3年。两个简单的多变量模型，都包括24小时光谱指数，能够识别患者进行性泵衰竭和猝死的风险较高，分别。夜间HRV（< 509 ms（2））功率降低至0.04 Hz [极低频（VLF）]以下，肺动脉楔压（PWP > 18 mm Hg）高，左心室射血分数（LVEF）低
Aims To assess whether analysis of heart rate variability (HRV) from 24 h Hotter recordings provides information about the mode of death (pump failure vs. sudden death) in chronic heart failure (CHF).Methods and results We analysed 24 h HRV in 330 consecutive CHF patients in sinus rhythm. Indices derived from time domain, spectral domain, and fractal analyses of 24 h automatic HRV were evaluated. Data from clinical assessment, echocardiography, right heart catheterization, exercise test, blood biochemical examination, and arrhythmia pattern were analysed. Patients were followed up for 3 years. Two simple multivariabte models, both including 24 h spectral indices, were able to identify patients at higher risk of progressive pump failure and sudden death, respectively. Depressed power of night-time HRV (< 509 ms(2)) below 0.04 Hz [very low frequency (VLF)], high pulmonary wedge pressure (PWP > 18 mm Hg) and low left ventricular ejection fraction (LVEF