An optoelectronic nose for the detection of toxic gases.
An optoelectronic nose for the detection of toxic gases.
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我们已经开发了一个简单的比色传感器阵列（CSA）的检测范围广泛的挥发性分析物，并将其应用于有毒气体的检测。该传感器由交叉响应纳米多孔颜料的一次性阵列组成，其颜色通过与分析物的各种化学相互作用而改变。虽然没有单一的化学反应颜料是特定于任何一种分析物，颜色变化的模式阵列是一个独特的分子指纹。19种不同的有毒工业化学品（TIC）在IDLH（立即危及生命或健康）浓度下暴露两分钟内的明显区别已被证明。每种分析物的定量很容易实现的基础上的颜色变化的阵列，并已证明了良好的检测限，一般低于PEL（允许的暴露限值）。使用标准化学计量学方法容易地实现TIC的鉴定，即，分层聚类分析（HCA），在140个试验中没有错误分类。
We have developed a simple colorimetric sensor array (CSA) for the detection of a wide range of volatile analytes and applied it to the detection of toxic gases. The sensor consists of a disposable array of cross-responsive nanoporous pigments whose colors are changed by diverse chemical interactions with analytes. Although no single chemically responsive pigment is specific for any one analyte, the pattern of color change for the array is a unique molecular fingerprint. Clear differentiation among 19 different toxic industrial chemicals (TICs) within two minutes of exposure at IDLH (immediately dangerous to life or health) concentration has been demonstrated. Quantification of each analyte is easily accomplished based on the color change of the array, and excellent detection limits have been demonstrated, generally below the PELs (permissible exposure limits). Identification of the TICs was readily achieved using a standard chemometric approach, i.e., hierarchical clustering analysis (HCA), with no misclassifications over 140 trials.