The microbicide tenofovir does not inhibit nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine samples.
The microbicide tenofovir does not inhibit nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine samples.
复制标题
杀菌剂替诺福韦不会抑制用于检测尿液样本中沙眼衣原体和淋病奈瑟菌的核酸扩增测试。
DOI：
10.1128/jcm.01867-07
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发表时间：
2008
影响因子：
9.4
通讯作者：
Gaydos,CharlotteA
中科院分区：
文献类型：
--
作者：
Wood,BillieJo;Rizzo-Price,Patricia;Holden,Jeff;Hardick,Andrew;Quinn,ThomasC;Gaydos,CharlotteA
使用Becton Dickinson ProbeTec、Gen-Probe Aptima Combo 2和Roche Amplicor检测沙眼衣原体和淋病奈瑟菌来检测替诺福韦和安慰剂的潜在抑制作用。将浓度为5%至0%的替诺福韦和安慰剂加入c的稀释剂中。trachomatisandN。球菌。未观察到明显的抑制作用。
The potential inhibitory effects of tenofovir and a placebo were examined using the Becton Dickinson ProbeTec, Gen-Probe Aptima Combo 2, and Roche Amplicor tests to detectChlamydia trachomatisandNeisseria gonorrhoeae. Concentrations of 5% to 0% of tenofovir and the placebo were added to dilutions ofC. trachomatisandN. gonorrhoeae. No appreciable inhibition was observed.