Cytotoxic flavonol glycosides from Triplaris cumingiana.
Cytotoxic flavonol glycosides from Triplaris cumingiana.
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来自 Triplaris cumingiana 的细胞毒性黄酮醇糖苷。
DOI:
10.1021/np049803g
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发表时间:
2005
期刊:
影响因子:
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通讯作者:
Gupta,MahabirP
中科院分区:
文献类型:
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作者:
Hussein,AhmedA;Barberena,Icela;Correa,Mireya;Coley,PhyllisD;Solis,PabloN;Gupta,MahabirP
Three new compounds, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl-4,6-bis-O-β-d-(3,4,5-trihydroxybenzoyl)glucopyranoside (1), 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl-5-O-α-l-(3,4,5-trihydroxybenzoyl)arabinofuranoside (2), and 2-hydroxy-4-O-α-l-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenylarabinofuranoside (3), were isolated from the young leaves ofTriplariscumingiana,together with two known compounds, quercetin 3-O-α-l-(5‘ ‘-O-galloyl)arabinofuranoside (4) and quercetin 3-O-β-d-(6‘ ‘-O-galloyl)glucopyranoside (5). The structures of1−3were established by spectroscopic methods. Compounds1−5were evaluated for their cytotoxic activities against the MCF-7, H-460, and SF-268 human cancer cell lines.