Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment
Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment
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DOI：
10.2147/ndt.s189905
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发表时间：
2019-01-01
影响因子：
3.2
通讯作者：
Timar, Bogdan
中科院分区：
文献类型：
--
作者：
Albai, Oana;Frandes, Mirela;Timar, Bogdan
背景：痴呆和认知功能障碍有许多原因。有强有力的证据表明，糖尿病（DM）会增加认知障碍和痴呆的风险。最佳血糖控制，糖尿病危险因素的识别，和预防方法是必不可少的，在预防认知complications.Aims：本研究的主要目的是建立糖尿病患者的认知功能障碍，照顾在糖尿病中心从蒂米什瓦拉。此外，我们还调查了我们组中痴呆的患病率以及参与轻度认知功能障碍（MCI）进展为demential.Patients和方法的危险因素：我们考虑了207例2型糖尿病（T2 DM）患者的样本，年龄在33岁至81岁之间，平均57.49（+/- 11.37）岁。我们根据简易精神状态检查（MMSE）测试以及心理测试、精神病学和神经学调查以及影像学检查确定了痴呆的诊断（计算机断层扫描和MRI）。结果：MCI患者占42.03%，平均年龄63（57.00-71.00）岁，比无MCI的患者年龄大，平均年龄52.00（45.00-61.00）岁，P
Background: Dementia and cognitive dysfunction have many causes. There is strong evidence that diabetes mellitus (DM) increases the risk of cognitive impairment and dementia. Optimal glycemic control, identification of diabetic risk factors, and prophylactic approach are essential in the prevention of cognitive complications.Aims: The main purpose of this study was to establish the cognitive impairment in DM patients, cared for in the Diabetes Center from Timisoara. Also, we investigated the prevalence of dementia in our group as well as the risk factors involved in the progression of mild cognitive impairment (MCI) to dementia.Patients and methods: We considered a sample of 207 type 2 DM (T2DM) patients, aged between 33 and 81 years, mean 57.49 (+/- 11.37) years. We established the diagnosis of dementia based on the Mini-Mental State Examination (MMSE) test, as well as on the psychological testing, psychiatric and neurological investigations, and imaging tests (computerized tomography and MRI).Results: A percentage of 42.03% of patients presented MCI, mean age 63 (57.00-71.00) years, being older than patients without MCI, mean age 52.00 (45.00-61.00) years, P