INSULIN, GLUCAGON, AND GLUCOSE EXHIBIT SYNCHRONOUS, SUSTAINED OSCILLATIONS IN FASTING MONKEYS
INSULIN, GLUCAGON, AND GLUCOSE EXHIBIT SYNCHRONOUS, SUSTAINED OSCILLATIONS IN FASTING MONKEYS
复制标题
DOI：
10.1126/science.401543
复制
发表时间：
1977-01-01
期刊：
影响因子：
56.9
通讯作者：
KALNASY, L
中科院分区：
文献类型：
--
作者：
GOODNER, CJ;WALIKE, BC;KALNASY, L
在禁食过夜的恒河猴中，葡萄糖、胰岛素和胰高血糖素的血浆浓度发生同步的、有规律的振荡。振荡显示平均9分钟的周期。胰岛素和胰高血糖素的振幅分别为葡萄糖的10倍和5倍。胰岛素在葡萄糖中循环，胰高血糖素在葡萄糖中循环。在狒狒的葡萄糖和胰岛素的振荡小于恒河猴，而在人，没有观察到有规律的振荡。
In overnight fasted rhesus monkeys, synchronous, regular oscillations occurred in the plasma concentrations of glucose, insulin and glucagon. The oscillations displayed a period averaging 9 min. The amplitudes for insulin and glucagon were 10 and 5 times greater than for glucose. Insulin cycled in and glucagon out of phase with glucose. In baboons oscillations of glucose and insulin were smaller than in rhesus monkeys, while in man, regular oscillations were not observed.