Use of intrathecal morphine for postoperative pain relief after elective laparoscopic colorectal surgery
Use of intrathecal morphine for postoperative pain relief after elective laparoscopic colorectal surgery
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DOI：
10.1046/j.1365-2044.2002.02873.x
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发表时间：
2002-12-01
期刊：
影响因子：
10.7
通讯作者：
Li, MKW
中科院分区：
文献类型：
--
作者：
Kong, SK;Onsiong, SMK;Li, MKW
近年来，腹腔镜手术已经变得很流行，但很少有研究解决这种手术的镇痛问题。我们对36例腹腔镜结直肠手术患者进行了前瞻性双盲随机试验，以确定鞘内吗啡对术后疼痛缓解的影响。除全身麻醉外，所有患者均接受蛛网膜下腔阻滞和局部麻醉。一组同时接受鞘内吗啡。术后采用患者自控镇痛（PCA）装置控制疼痛，采用视觉模拟评分（VAS）进行疼痛评估。鞘内注射吗啡组吗啡用量明显减少。联合麻醉技术对心血管无不良影响。恶心和呕吐仍然是鞘内注射吗啡的主要副作用，但这很容易用止吐剂治疗。
Laparoscopic surgery has become popular in recent years, but few studies have addressed analgesia for this type of surgery. We conducted a prospective double-blind randomised trial on 36 cases of laparoscopic colorectal surgery to determine the influence of intrathecal morphine on postoperative pain relief. All patients received a subarachnoid block with local anaesthetic in addition to general anaesthesia. One group also received intrathecal morphine. A patient-controlled analgesic (PCA) device was prescribed for pain control postoperatively and the visual analogue score (VAS) was used for pain assessment. The group who received intrathecal morphine used significantly less morphine. There were no adverse cardiovascular effects of the combined anaesthetic technique. Nausea and vomiting remained the main side-effect of intrathecal morphine but this was easily treated with anti-emetics.