Carcinomatous Meningitis in Cancer of the Uterine Cervix
Carcinomatous Meningitis in Cancer of the Uterine Cervix
复制标题
子宫颈癌中的癌性脑膜炎
DOI：
10.1023/b:neon.0000040836.20884.fc
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发表时间：
2004
影响因子：
3.9
通讯作者：
C. V. van Groeningen
中科院分区：
文献类型：
--
作者：
M. Rentinck;H. Schrijver;E. Kneppers;J. Zijlmans;C. V. van Groeningen
癌性脑膜炎在宫颈癌中极为罕见。癌性脑膜炎的诊断是一个困难的，当临床症状是有限的，放射影像学是正常的。脑脊液中恶性细胞的显示仍然是建立诊断的金标准。对于没有大体积疾病的患者，可以用放射治疗，癌性脑膜炎的标准治疗是化疗，可以鞘内给药。尽管预后不良，治疗可能会导致有效的姑息治疗。我们描述了一个54岁的病人谁被诊断为癌性脑膜炎的过程中转移性宫颈癌和谁回应管理鞘内甲氨蝶呤。
Carcinomatous meningitis is extremely rare in cervical cancer. The diagnosis of carcinomatous meningitis is a difficult one when clinical symptoms are limited and radiographic imaging is normal. Demonstration of malignant cells in the cerebrospinal fluid remains the gold standard to establish the diagnosis. For patients without bulky disease who can be treated with radiotherapy, standard treatment for carcinomatous meningitis is chemotherapy, which may be administered intrathecally. Despite the poor prognosis, treatment may result in effective palliation. We describe a 54-year-old patient who was diagnosed with carcinomatous meningitis in the course of metastatic cervical cancer and who responded to administration of intrathecal methotrexate.