Stromal invasion by carcinoma of the cervix: Assessment with dynamic MR imaging
Stromal invasion by carcinoma of the cervix: Assessment with dynamic MR imaging
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DOI：
10.2214/ajr.168.6.9168730
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发表时间：
1997-06-01
影响因子：
5
通讯作者：
Sakai, K
中科院分区：
文献类型：
--
作者：
Seki, H;Azumi, R;Sakai, K
目的，本研究的目的是评估动态 MR 成像在评估宫颈癌间质侵犯深度方面的作用，并将动态 MR 成像与 T2 加权和对比增强 T1 加权 MR 成像进行比较。 对象和方法，对 41 名临床上被认为局限于宫颈的癌症患者进行了 T2 加权、动态和对比增强检查手术前 T1 加权 MR 成像。我们评估了子宫颈和肿瘤的增强模式，并通过 MR 成像评估了间质浸润的程度。间质侵犯程度分为两组：浅表病变（无间质侵犯或侵犯小于或等于3毫米）和深层侵犯（间质侵犯>3毫米）。然后我们将这些 MR 结果与间质浸润深度的组织学结果进行比较。结果。动态MR成像显示，深部浸润的宫颈癌在早期动态期表现为局灶性强化区域。宫颈上皮和间质强化不太明显。在区分深层浸润和浅表病变时，我们发现 T2 加权 MR 图像、动态 MR 图像和对比增强 T1 加权 MR 图像的准确性分别为 76%、98% 和 63%。特别是，动态 MR 图像对 3.1-5.0 nm 间质浸润的检测能力明显高于其他技术：使用 T2 加权 MR 图像，我们在 23% 的患者中看到 3.1-5.0 mm 的间质浸润；动态 MR 图像，92%；对比增强 T1 加权 MR 图像则没有。三种 MR 技术均未发现浅表疾病。 结论。我们认为，在评估宫颈癌浸润深度时，动态MR成像优于T2加权MR成像和对比增强T1加权MR成像。
OBJECTIVE, The purpose of this study was to evaluate dynamic MR imaging in assessing the depth of stromal invasion by carcinoma of the cervix and to compare dynamic MR imaging with T2-weighted and contrast-enhanced T1-weighted MR imaging.SUBJECTS AND METHODS, Forty-one patients with carcinoma that was clinically considered to be confined to the cervix were examined with T2-weighted, dynamic, and contrast-enhanced T1-weighted MR imaging before surgery. We evaluated enhancement patterns of the cervix and tumor and assessed the degree of stromal invasion with MR imaging. The degree of stromal invasion was divided into two groups: superficial disease (no stromal invasion or invasion of less than or equal to 3 mm) and deep invasion (>3 mm of stromal invasion). Then we compared these MR findings with histologic results for the depth of stromal invasion.RESULTS. With dynamic MR imaging, cervical carcinoma with deep invasion was seen as a focal enhanced area in the early dynamic phase. The cervical epithelium and stroma enhanced less vividly. In distinguishing deep invasion from superficial disease, we found the accuracy of T2-weighted MR images, dynamic MR images, and contrast-enhanced T1-weighted MR images to be 76%, 98%, and 63%, respectively. In particular, the detectability of 3.1-5.0 nm of stromal invasion with dynamic MR images was significantly higher than that wits the other techniques: with T2-weighted MR images, we saw 3.1-5.0 mm of stromal invasion in 23% of patients; with dynamic MR images, in 92%; and with contrast-enhanced T1-weighted MR images, in none. Superficial disease was not revealed with any of the three MR techniques.CONCLUSION. We believe that dynamic MR imaging is superior to T2-weighted MR imaging and contrast-enhanced T1-weighted MR imaging when assessing the depth of invasion of cervical carcinoma.