Factors relating to the infant's last sleep environment in sudden infant death syndrome in the Republic of Ireland

Factors relating to the infant's last sleep environment in sudden infant death syndrome in the Republic of Ireland
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DOI:
10.1136/adc.88.12.1058
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发表时间:
2003-12-01
影响因子:
5.2
通讯作者:
Matthews, T
Matthews, T
中科院分区:
医学2区
文献类型:
--
作者:
McGarvey, C;McDonnell, M;Matthews, T

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目的:确定危险因素婴儿猝死综合征(SIDS)在睡眠环境中的Irishinfants.Methods:一项为期五年的人口为基础的病例对照研究,父母进行访谈,为每个案件和三个对照匹配的年龄,出生地,和最后的睡眠时间。结果:在多变量分析中,共睡显著增加了SIDS的风险,无论是作为一种常规的做法,(调整后OR 4.31; 95% CI 1.07至17.37)和最后一次睡眠期间(调整后OR 16.47; 95% CI 3.73至72.75)。相关风险取决于母亲吸烟(OR 21.84; 95%CI 2.27 - 209.89),对于大于或等于20周龄的婴儿无显著性差异(OR 2.63; 95% CI 0.49至70.10)或放回自己的婴儿床/床上睡觉(OR 1.07; 95% CI 0.21至5.41)。当调整混杂变量(包括母亲吸烟和社会劣势)的影响时,使用tog值大于或等于10的枕头、羽绒被和床上用品不是显著的风险因素。然而,俯卧睡姿仍然是一个显着的SIDS的危险因素,在婴儿使用安抚奶嘴,没有安抚奶嘴使用在最后一个睡眠期间也显着增加了SIDS的风险(OR 5.83; CI 2.37至14.36)。结论:共睡应避免婴儿谁是,20周龄,或母亲吸烟在怀孕期间。俯卧位仍然是一些SIDS死亡的一个因素,安抚奶嘴的使用和SIDS之间的关系是一个复杂的变量,需要进一步研究。
Aim: To identify risk factors for sudden infant death syndrome ( SIDS) in the sleeping environment of Irish infants.Methods: A five year population based case- control study with parental interviews conducted for each case and three controls matched for age, place of birth, and last sleep period. A total of 203 SIDS cases and 622 control infants born 1994 - 98 were studied.Results: In a multivariate analysis, co- sleeping significantly increased the risk of SIDS both as a usual practice ( adjusted OR 4.31; 95% CI 1.07 to 17.37) and during the last sleep period ( adjusted OR 16.47; 95% CI 3.73 to 72.75). The associated risk was dependent on maternal smoking ( OR 21.84; 95% CI 2.27 to 209.89), and was not significant for infants who were greater than or equal to 20 weeks of age ( OR 2.63; 95% CI 0.49 to 70.10) or placed back in their own cot/ bed to sleep ( OR 1.07; 95% CI 0.21 to 5.41). The use of pillows, duvets, and bedding with tog value greater than or equal to 10 were not significant risk factors when adjusted for the effects of confounding variables, including maternal smoking and social disadvantage. However, the prone sleeping position remains a significant SIDS risk factor, and among infants using soothers, the absence of soother use during the last sleep period also significantly increased the SIDS risk ( OR 5.83; CI 2.37 to 14.36).Conclusion: Co- sleeping should be avoided in infants who are,20 weeks of age, or whose mothers smoked during pregnancy. The prone position remains a factor in some SIDS deaths, and the relation between soother use and SIDS is a complex variable requiring further study.