A STUDY OF NATURALLY-OCCURRING FELINE CORONAVIRUS INFECTIONS IN KITTENS
A STUDY OF NATURALLY-OCCURRING FELINE CORONAVIRUS INFECTIONS IN KITTENS
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DOI：
10.1136/vr.130.7.133
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发表时间：
1992-02-15
影响因子：
2.2
通讯作者：
JARRETT, O
中科院分区：
文献类型：
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作者：
ADDIE, DD;JARRETT, O
猫冠状病毒是猫的常见感染，病毒抗体的高流行表明，特别是在多猫家庭中。 大约 5% 至 12% 的血清阳性猫会患上典型的猫传染性腹膜炎。 对血清阳性猫家庭出生的小猫进行的一项调查表明，存在健康的冠状病毒携带者。 血清阴性动物似乎不排泄病毒。 没有特定的抗体滴度与携带者状态相关，一些携带者猫随后变得血清阴性。 小猫的管理很大程度上影响它们是否被感染，母源抗体似乎赋予了一定程度的保护。 目前，猫传染性腹膜炎病毒和猫肠道冠状病毒只能通过感染猫舍不同的临床病史来区分。 在这项调查中，猫传染性腹膜炎病例发生在最初表现为肠炎的家庭的小猫中，反之亦然。 因此，在流行病学上没有发现差异。
Feline coronavirus is a common infection in cats, as indicated by the high prevalence of antibodies against the virus, especially in multicat households. Approximately 5 to 12 per cent of seropositive cats develop classical feline infectious peritonitis. A survey of kittens born into households of seropositive cats demonstrated the existence of healthy coronavirus carriers. Seronegative animals did not appear to excrete virus. No specific antibody titre could be linked to carrier status and some carrier cats subsequently became seronegative. The management of the kittens strongly influence whether they became infected, and some degree of protection appeared to be conferred by maternally derived antibody. At present, feline infectious peritonitis virus and feline enteric coronavirus can only be differentiated by their different clinical histories in infected catteries. In this survey, cases of feline infectious peritonitis occurred in kittens from households where the initial presentation had been enteritis and vice versa. Therefore no difference in epidemiology could be found.