Immune complex type glomerulonephritis in cirrhosis of the liver.
Immune complex type glomerulonephritis in cirrhosis of the liver.
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肝硬化免疫复合物型肾小球肾炎。
DOI：
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发表时间：
1975
影响因子：
6
通讯作者：
J. Bariéty
中科院分区：
文献类型：
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作者：
P. Callard;G. Feldmann;D. Prandi;M. Bélair;C. Mandet;Y. Weiss;P. Druet;J. Benhamou;J. Bariéty
在10例肝硬化患者中有9例检测到肾小球病变：这些病变包括a）基底膜样物质增厚，B）系膜区和毛细血管壁中的电子致密沉积物，c）膜样物质和某些沉积物中的圆形稀疏区，以及d）沉积物中存在伊加、IgG和/或IgM和/或C3。这四种异常的联合似乎是“肾小球肾炎”的特征。“这些沉积物可能是聚集的免疫球蛋白或循环免疫复合物在肾小球中沉淀的结果。
Glomerular lesions were detected in 9 of 10 patients with liver cirrhosis: these lesions consisted of a) thickening of basement-membrane-like material, b) electron-dense deposits in mesangial areas and in capillary walls, c) round areas of rarefaction in the membrane-like material and in some deposits, and d) presence of IgA, with IgG and/or IgM and/or C3, in the deposits. The association of these four abnormalities seems to be characteristic of "cirrhotic glomerulonephritis." The deposits could be the result of precipitation in the glomeruli of either aggregated immunoglobulins or circulating immune complexes.