Induction of telithromycin resistance by erythromycin in isolates of macrolide-resistant Staphylococcus spp.
Induction of telithromycin resistance by erythromycin in isolates of macrolide-resistant Staphylococcus spp.
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DOI：
10.1128/aac.49.7.3059-3061.2005
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发表时间：
2005-07-01
影响因子：
4.9
通讯作者：
Jorgensen, JH
中科院分区：
文献类型：
--
作者：
Davis, KA;Crawford, SA;Jorgensen, JH
对葡萄球菌分离株进行了大环内酯诱导的对特利霉素的耐药性检测。所有大环内酯耐药菌株均表现为特利霉素d形带。该结果没有区分由于外排机制（msrA）或核糖体靶修饰（ermA或ermC）引起的耐药。葡萄球菌可诱导的特利霉素耐药似乎与可诱导的克林霉素耐药不同。
Staphylococcal isolates were examined for possible macrolide-inducible resistance to telithromycin. All macrolide-resistant isolates demonstrated telithromycin D-shaped zones. This result did not discriminate between resistance due to an efflux mechanism (msrA) or a ribosomal target modification (ermA or ermC). Inducible telithromycin resistance in staphylococci does not appear to be analogous to inducible clindamycin resistance.