Radial Sliding-Window Magnetic Resonance Angiography (MRA) With Highly-Constrained Projection Reconstruction (HYPR)
Radial Sliding-Window Magnetic Resonance Angiography (MRA) With Highly-Constrained Projection Reconstruction (HYPR)
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DOI：
10.1002/mrm.21888
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发表时间：
2009-05-01
影响因子：
3.3
通讯作者：
Carroll, Timothy J.
中科院分区：
文献类型：
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作者：
Jeong, Hyun J.;Cashen, Ty A.;Carroll, Timothy J.
血流动态成像需要足够的时间分辨率，这对于各种颅内血管疾病（如动静脉畸形（AVMs）和动脉瘤）的准确诊断和治疗至关重要。高约束投影重建（HYPR）最近成为高速对比增强磁共振血管造影（CE-MRA）的一种技术。HYPR通过优先加权径向投影提供高帧率，同时使用高信噪比复合材料保持信噪比（SNR）。与先前开发的径向滑动窗技术相比，使用标准滤波反投影或重网格方法，量化了HYPR对信噪比、噪比（CNR）和时间模糊的影响。通过计算机仿真，研究了HYPR处理对图像误差和时间信息的影响。此外，对血管造影证实的avm患者进行体内成像，以测量各种HYPR参数的改变对信噪比的影响以及时间信息的保真度。图像由介入放射科医生在盲读中评分，并与x射线数字减影血管造影（DSA）进行比较。研究发现，与径向滑动窗MRA相比，通过选择正确的参数，可以实现信噪比和动态信息的适度改善。中华医学杂志，2009,31(1):391 - 391。(C) 2009 Wiley-Liss, Inc。
Sufficient temporal resolution is required to image the dynamics of blood flow, which may be critical for accurate diagnosis and treatment of various intracranial vascular diseases, such as arteriovenous malformations (AVMs) and aneurysms. Highly-constrained projection reconstruction (HYPR) has recently become a technique of interest for high-speed contrast-enhanced magnetic resonance angiography (CE-MRA). HYPR provides high frame rates by preferential weighting of radial projections while maintaining signal-to-noise ratio (SNR) by using a high SNR composite. An analysis was done to quantify the effects of HYPR on SNR, contrast-to-noise ratio (CNR), and temporal blur compared to the previously developed radial sliding-window technique using standard filtered backprojection or regridding methods. Computer simulations were performed to study the effects of HYPR processing on image error and the temporal information. Additionally, in vivo imaging was done on patients with angiographically confirmed AVMs to measure the effects of alteration of various HYPR parameters on SNR as well as the fidelity of the temporal information. The images were scored by an interventional radiologist in a blinded read and were compared with X-ray digital subtraction angiography (DSA). It was found that with the right choice of parameters, modest improvements in both SNR and dynamic information can be achieved as compared to radial sliding-window MRA. Magn Reson Med 61:1103-1113, 2009. (C) 2009 Wiley-Liss, Inc.