Advances in DNA Supramolecular Hydrogels for Tissue Engineering
Advances in DNA Supramolecular Hydrogels for Tissue Engineering
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DOI：
10.1002/mabi.202200152
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Liu Huajie
中科院分区：
文献类型：
--
作者：
Chen Chun;Zhou Jiaying;Chen Jie;Liu Huajie
Deoxyribonucleic acid (DNA) is a biological macromolecule that plays a genetic role in cells. DNA molecules with specific recognition, self-assembly capabilities, and sequence programmability have become an excellent construction material for micro- and nanostructures. Based on DNA self-assembly technology, a series of molecular devices and materials are constructed. Among them, DNA hydrogels with the advantages of good biocompatibility, biodegradability, and containing designable stimuli-responsive units have attracted much attention. This review introduces the formation strategy of DNA supramolecular hydrogels, and focuses on its applications in tissue engineering, including cell encapsulation, cell culture, cell capture and release, wound dressings, and tissue growth. The unique properties and application prospects of DNA supramolecular hydrogels in tissue engineering are also discussed.
