RELATIONSHIPS BETWEEN LEFT VENTRICULAR EJECTION TIME, STROKE VOLUME, AND HEART RATE IN NORMAL INDIVIDUALS AND PATIENTS WITH CARDIOVASCULAR DISEASE
RELATIONSHIPS BETWEEN LEFT VENTRICULAR EJECTION TIME, STROKE VOLUME, AND HEART RATE IN NORMAL INDIVIDUALS AND PATIENTS WITH CARDIOVASCULAR DISEASE
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DOI：
10.1016/0002-8703(61)90403-3
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发表时间：
1961-01-01
影响因子：
4.8
通讯作者：
ROEHLL, WH
中科院分区：
文献类型：
--
作者：
WEISSLER, AM;PEELER, RG;ROEHLL, WH
研究了正常人和心血管疾病患者的射血时间、心率和每搏输出量之间的关系。射血时间是通过颈动脉或锁骨下脉搏描记来测量的，每搏输出量是通过直接测量血流量得出的。在正常个体中，射血时间与心率成反比，与每搏输出量成正比。在非瓣膜性心脏病和心力衰竭中，射血时间相对于心率通常较低，但相对于每搏输出量往往落在正常范围内。在充血性心力衰竭中观察到的每搏输出量水平，左心室射血率平均正常。在主动脉瓣关闭不全和孤立性主动脉瓣狭窄中观察到射血时间相对于每搏输出量的延长。射血时间延长的程度与主动脉瓣膜疾病的严重程度密切相关。在二尖瓣疾病（包括孤立性二尖瓣狭窄）以及轻度至中度二尖瓣反流中，射血时间相对于每搏输出量落在正常范围内。在严重高血压疾病中，射血时间相对于每搏输出量落在正常或低正常范围内。在心包疾病中，观察到射血时间的异常阶段性呼吸变化。目前对心脏射血时间现象的观察表明这些技术在评估患有各种心血管疾病的患者中的实际应用。
The relationships between the ejection time, heart rate, and stroke volume in normal individuals and in patients with cardiovascular disorders were investigated. Ejection time was measured from the carotid or subclavian pulse tracing, and stroke volume was derived from direct measurements of blood flow. In normal individuals, ejection time varied inversely with heart rate and directly with stroke volume. In nonvalvular heart disease and cardiac failure, ejection time was usually low relative to heart rate but tended to fall within normal limits relative to stroke volume. At the level of stroke volume observed in congestive heart failure, the mean rate of left ventricular ejection was normal. Prolongation of ejection time relative to stroke volume was observed in aortic insufficiency and in isolated aortic stenosis. The degree of prolongation in ejection time was well correlated with the severity of the aortic valvular disease. In mitral valvular disease, including isolated mitral stenosis, as well as in mild to moderate mitral regurgitation, ejection time fell within the normal range relative to stroke volume. In severe hypertensive disease, ejection time fell within the normal or low normal range relative to stroke volume. In pericardia disease an abnormal phasic respiratory variation in ejection time was observed. The present observations on temporal phenomena in cardiac ejection suggests the practical application of these techniques in the evaluation of patients with various cardiovascular disorders.