Rejoinder: ‘Gene hunting with hidden Markov model knockoffs’

Rejoinder: ‘Gene hunting with hidden Markov model knockoffs’
复制标题

DOI:
10.1093/biomet/asy075
复制
发表时间:
2019-02
期刊:
影响因子:
2.7
通讯作者:
Matteo Sesia;C. Sabatti;E. Candès
Matteo Sesia;C. Sabatti;E. Candès
中科院分区:
数学2区
文献类型:
--
作者:
Matteo Sesia;C. Sabatti;E. Candès

文献摘要

被引文献

相似文献

在这篇论文中,我们从Bottolo&Richardson(2019);Jewell&Witten(2019);Rosenblatt等人的讨论开始,深化和扩大了对仿冒方法用于全基因组关联研究的可能优势的思考(Sesia等人,2018)。(2019)和Marchini(2019)。讨论者提出了一些重要的观点,要么与仿冒方法有关,要么与其在遗传学研究中的具体应用有关。在下文中,我们提供一些澄清,提到相关的最新发展,并强调一些仍然悬而未决的问题。
In this paper we deepen and enlarge the reflection on the possible advantages of a knockoff approach to genome wide association studies (Sesia et al., 2018), starting from the discussions in Bottolo & Richardson (2019); Jewell & Witten (2019); Rosenblatt et al. (2019) and Marchini (2019). The discussants bring up a number of important points, either related to the knockoffs methodology in general, or to its specific application to genetic studies. In the following we offer some clarifications, mention relevant recent developments and highlight some of the still open problems.