Autonomic and central nervous system effects of lead in female glass workers in China.

Autonomic and central nervous system effects of lead in female glass workers in China.
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铅对中国女性玻璃工人自主和中枢神经系统的影响。

DOI:
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发表时间:
1995
影响因子:
3.5
通讯作者:
Shi
Shi
中科院分区:
医学4区
文献类型:
--
作者:
Katsuyuki Murata;Shunichi Araki;K. Yokoyama;Kazuo Nomiyama;H. Nomiyama;Yong;Shi

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为探讨铅对植物神经和中枢神经系统功能的影响,对36名铅作业女工(接触组)和15名纺织女工(非接触组)进行了心电图R-R间期变异性(CVRR)、视觉诱发电位(VEP)和脑干听觉诱发电位(BAEP)的检测。C-CVLF,C-CVHF(CVRR的两个分量CV,分别反映交感神经和副交感神经活动),LF/HF比(交感神经迷走神经平衡的指标),也计算了从成分谱功率的自回归谱和成分分析。接触组从事玻璃工作2-17年,平均7.8年。接触组血铅浓度为25.8-79.3(平均55.6)微克/分升,未接触组为4.7-8.6(平均6.3)微克/分升。接触组CVRR、C-CVLF、C-CVHF、LF/HF比值均显著低于未接触组。此外,暴露组有更多的投诉的主观症状和体征比未暴露组。两组VEP和BAEP潜伏期无显著性差异。这表明,自主神经功能比视觉和听觉神经功能更容易受到铅的影响;铅对交感神经活动的影响比副交感神经活动更强烈。
To clarify the effects of lead on autonomic and central nervous system functions, electrocardiographic R-R interval variability (CVRR) as well as visual and brainstem auditory evoked potentials (VEP and BAEP) were measured in 36 female workers exposed to lead (exposed group) and in 15 female textile workers (unexposed group). The C-CVLF, C-CVHF (two component CVs of the CVRR reflecting sympathetic and parasympathetic activities, respectively), and LF/HF ratio (indicator of sympatho-vagal balance) were also computed from component spectral powers by means of autoregressive spectral and component analyses. The exposed group had engaged in glass work for 2-17 (mean 7.8) years. Blood lead (BPb) concentrations were 25.8-79.3 (mean 55.6) micrograms/dl in the exposed group and 4.7-8.6 (mean 6.3) micrograms/dl in the unexposed group. The CVRR, C-CVLF, C-CVHF, and LF/HF ratio in the exposed group were significantly lower than those in the unexposed group. Also, the exposed group had more complaints of subjective symptoms and signs than did the unexposed group. On the other hand, no significant differences in either VEP or BAEP latencies were found between the two groups. It is suggested that autonomic nervous function is more susceptible to lead than visual and auditory nervous functions; lead affects sympathetic activity more strongly than parasympathetic activity.
DOI: 10.1152/ajpheart.1985.248.1.h151
发表时间: 1985-01-01
影响因子: --
作者:
POMERANZ, B;MACAULAY, RJB;BENSON, H
通讯作者: BENSON, H
DOI: 10.1016/0013-4694(81)90052-3
发表时间: 1981-10
期刊: Electroencephalography and clinical neurophysiology
影响因子: --
作者:
D. Otto;V. Benignus;V. Benignus;K. E. Muller;C. Barton
通讯作者: D. Otto;V. Benignus;V. Benignus;K. E. Muller;C. Barton
DOI: --
发表时间: 1993
期刊: Neurotoxicology
影响因子: 3.4
作者:
D. Otto;D. Fox
通讯作者: D. Otto;D. Fox