PRENATAL AND LACTATIONAL TRANSMISSION OF TOXOCARA-CANIS AND ANCYLOSTOMA-CANINUM - EXPERIMENTAL-INFECTION OF THE BITCH BEFORE PREGNANCY
PRENATAL AND LACTATIONAL TRANSMISSION OF TOXOCARA-CANIS AND ANCYLOSTOMA-CANINUM - EXPERIMENTAL-INFECTION OF THE BITCH BEFORE PREGNANCY
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DOI：
10.1016/0020-7519(85)90104-3
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发表时间：
1985-01-01
影响因子：
4
通讯作者：
ROBERSON, EL
中科院分区：
文献类型：
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作者：
BURKE, TM;ROBERSON, EL
饲养 5 只无寄生虫和 5 只实验性感染的小猎犬母犬（6000 只经口感染犬毛虫卵和 2500 只犬毛虫幼虫皮下注射）比格犬母犬，以便成对母犬（1 只未感染，1 只感染）同时产仔。受感染的母犬产下的幼崽在出生时就被取出，由配对的未受感染的母犬喂养，直到 4 周大时，对幼崽进行尸检以确定它们在产前从受感染的母亲那里获得的寄生虫数量。无寄生虫的母犬所生的幼崽由受感染的母犬喂养，直到 4 周龄时进行尸检，以确定通过哺乳途径传播的寄生虫数量。在通过任一途径传播给幼犬的 680 只蛔虫中，98.5% 是在产前传播的，1.5% 是在哺乳期传播的。 2746 只钩虫仅通过哺乳途径传播给 22 只幼犬，而受感染母犬所生的 25 只幼犬均未发生这种寄生虫的产前传播。
Breeding of 5 parasite-free and 5 experimentally infected (6000 T. canis eggs orally and 2500 A. caninum larvae s.c.) beagle bitches was done so that pairs of bitches (1 uninfected, 1 infected) whelped simultaneously. Pups born to an infected bitch were removed at birth and nursed by the paired uninfected bitch until 4 wk of age when pups were necropsied to determine the number of parasites they had acquired prenatally from their infected mother. Pups born to the parasite-free bitch were nursed by the infected bitch until necropsied at 4 wk of age to determine the number of parasites passed via the lactational route. Of 680 ascarids transmitted to pups by either route, 98.5% were transmitted prenatally and 1.5% lactationally. Transmission of 2746 hookworms to 22 pups occurred solely by the lactational route, prenatal transmission of this parasite did not occur in any of the 25 pups born to infected bitches.