Comparison of three methods of intraocular pressure measurement and their relation to central corneal thickness
Comparison of three methods of intraocular pressure measurement and their relation to central corneal thickness
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DOI：
10.1038/eye.2010.11
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发表时间：
2010-07-01
期刊：
影响因子：
3.9
通讯作者：
Hammond, C. J.
中科院分区：
文献类型：
--
作者：
Carbonaro, F.;Andrew, T.;Hammond, C. J.
目的本研究的目的是比较“金标准”Goldmann眼压计（GAT）与眼反应分析仪（ORA）和动态轮廓眼压计（DCT）的可靠性。患者和方法从伦敦圣托马斯医院的TwinsUK（英国成人双胞胎登记处）共招募了694名受试者。采用GAT、ORA和DCT测量眼压（IOP）。使用Bland-Altman方法评估三种方法之间的一致性。使用重复性系数和同一只眼睛第一次和第二次读数之间的变异系数来评估可靠性。结果平均年龄57.5岁（SD 13.1，范围16.1 ~ 88.5）。使用右眼两次读数的平均值计算的平均IOPs如下：Goldmann (GAT), 14.1 +/- 2.8 mm Hg；IOPg (ORA), 15.9 +/- 3.2 mm Hg；IOPcc (ORA), 16.6 +/- 3.2 mm Hg；和DCT， 16.9 +/- 2.7 mm Hg。95%的一致性限为ORA (IOPcc): GAT, -2.07 ~ 7.18 mm Hg；DCT: GAT, -0.49 ~ 6.21 mmhg；DCT: ORA (IOPcc), -3.01 ~ 4.85 mm Hg。三种血压计的变异系数分别为GAT， 8.3%；奥拉,8.2%;DCT, 6.3%。GAT重复性系数为3.4 mm Hg， ORA重复性系数为3.57 mm Hg， DCT重复性系数为3.09 mm Hg。GAT和ORA （IOPg）读数与角膜中央厚度呈正相关(P
Purpose The purpose of this study was to compare the reliability of the 'gold standard' Goldmann applanation tonometer (GAT), with that of the ocular response analyser (ORA), and the dynamic contour tonometer (DCT).Patients and methods A total of 694 subjects were recruited to participate from the TwinsUK (UK Adult Twin Registry) at St Thomas' Hospital, London. Intraocular pressure (IOP) was measured using GAT, ORA, and the DCT. The agreement between the three methods was assessed using the Bland-Altman method. Repeatability coefficients and coefficient of variation between first and second readings of the same eye were used to assess reliability.Results Mean age was 57.5 years (SD, 13.1; range, 16.1-88.5). The mean IOPs, calculated using the mean of two readings from the right eye were as follows: Goldmann (GAT), 14.1 +/- 2.8 mm Hg; IOPg (ORA), 15.9 +/- 3.2 mm Hg; IOPcc (ORA), 16.6 +/- 3.2 mm Hg; and DCT, 16.9 +/- 2.7 mm Hg. The 95% limits of agreement were for ORA (IOPcc): GAT, -2.07 to 7.18 mm Hg; for DCT: GAT, -0.49 to 6.21 mm Hg; and for DCT: ORA (IOPcc), -3.01 to 4.85 mm Hg. Coefficients of variation for the three tonometers were GAT, 8.3%; ORA, 8.2%; DCT, 6.3%. The repeatability coefficients were 3.4 mm Hg for GAT, 3.57 mm Hg for ORA and 3.09 mm Hg for DCT. GAT and ORA (IOPg) readings showed a positive correlation with central corneal thickness (P