Voice acoustical measurement of the severity of major depression
Voice acoustical measurement of the severity of major depression
复制标题
DOI：
10.1016/j.bandc.2004.05.003
复制
发表时间：
2004-10-01
影响因子：
2.5
通讯作者：
Snyder, PJ
中科院分区：
文献类型：
--
作者：
Cannizzaro, M;Harel, B;Snyder, PJ
许多实证研究已经证明了声音和言语的可量化和客观声学测量与重度抑郁症严重程度的临床主观评级之间的关系。为了进一步探讨这种关系，言语样本是从结构化访谈的录像带中提取的，这些访谈是在使用17项汉密尔顿抑郁评定量表（HDRS;汉密尔顿，1960）时进行的。从7名受试者（5名男性，2名女性）的录像带，已被用来培训专家评分的管理和评分的HDRS的试点数据。几个语音样本被隔离为每个主题和处理，以获得声学测量。选择声学测量的基础上，他们与HDRS评级的症状严重程度，在理想的语音记录条件下，在以前的研究。我们的研究结果证实了早期的报告，说话速度是很好的相关性（负）与HDRS分数，具有很强的相关性和几乎显着的趋势，为音高变异性的措施。暂停时间百分比和HDRS评分之间也存在中度成对相关性，尽管这种关系在统计学上不显著。这项横断面研究的结果进一步证明了声音和语音信号分析客观跟踪抑郁症严重程度的能力。在本案中，有人建议，这种关系是强大的，足以被发现，尽管不太理想的记录条件和设备，在原始录像带记录期间使用。语音声学分析可以为抑郁症的标准临床访谈提供有力的补充。这些措施的使用增加了可用于探索重性抑郁症的神经生物学基础的技术范围，它的治疗，以及控制言语产生的运动，认知和情感方面的系统的动态相互作用。(C)2004年爱思唯尔公司All rights reserved.
A number of empirical studies have documented the relationship between quantifiable and objective acoustical measures of voice and speech, and clinical subjective ratings of severity of Major Depression. To further explore this relationship, speech samples were extracted from videotape recordings of structured interviews made during the administration of the 17-item Hamilton Depression Rating Scale (HDRS; Hamilton, 1960). Pilot data were obtained from seven subjects (five males, two females) from videotapes that have been used to train expert raters on the administration and scoring of the HDRS. Several speech samples were isolated for each subject and processed to obtain the acoustic measurements. Acoustic measures were selected on the basis that they were correlated with HDRS ratings of symptom severity as seen under ideal voice recording conditions in previous studies. Our findings corroborate earlier reports that speaking rate is well correlated (negatively) with HDRS scores, with a strong correlation and nearly significant trend seen for the measure of pitch variability. A moderate pairwise correlation between percent pause time and HDRS score was also revealed, although this relationship was not statistically significant. The results from this cross-sectional study further demonstrate the ability of voice and speech signal analyses to objectively track severity of depression. In the present case, it is suggested that this relationship is robust enough to be found despite the less than ideal recording conditions and equipment used during the original videotape recording. Voice acoustical analyses may provide a powerful compliment to the standard clinical interview for depression. Use of such measures increases the range of techniques that are available to explore the neurobiological substrates of Major Depression, its treatment, and the dynamic interplay of the systems that govern the motor, cognitive, and emotional aspects of speech production. (C) 2004 Elsevier Inc. All rights reserved.