Health equality, race and pharmacogenomics.
Health equality, race and pharmacogenomics.
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DOI：
10.1111/bcp.14983
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发表时间：
2022-01
影响因子：
3.4
通讯作者：
Lee SS
中科院分区：
文献类型：
--
作者：
Magavern EF;Gurdasani D;Ng FL;Lee SS
药物基因组学正越来越多地进入主流临床实践。在人口分层的历史和社会背景下，必须认真考虑将不同的人口纳入研究、翻译和实施，以确保这导致改善所有人的医疗保健，而不是增加健康差距。这篇综述对药物基因组学中多样性的当前作用采取了广泛而关键的方法，并解决了潜在的陷阱，以提高处方医生的认识。它还强调了证据差距，并提出了可能最大限度地减少负面影响和促进健康平等的方法。
Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful consideration must be paid to inclusion of diverse populations in research, translation and implementation, in the historical and social context of population stratification, to ensure that this leads to improvements in healthcare for all rather than increased health disparities. This review takes a broad and critical approach to the current role of diversity in pharmacogenomics and addresses potential pitfalls in order to raise awareness for prescribers. It also emphasizes evidence gaps and suggests approaches that may minimize negative consequences and promote health equality.
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影响因子：
2.1
作者：
Hikino, Keiko;Fukunaga, Koya;Mushiroda, Taisei
通讯作者：
Mushiroda, Taisei
DOI：
10.1056/nejmoa1310669
发表时间：
2013-12-12
期刊：
The New England journal of medicine
影响因子：
--
作者：
Kimmel SE;French B;Kasner SE;Johnson JA;Anderson JL;Gage BF;Rosenberg YD;Eby CS;Madigan RA;McBane RB;Abdel-Rahman SZ;Stevens SM;Yale S;Mohler ER 3rd;Fang MC;Shah V;Horenstein RB;Limdi NA;Muldowney JA 3rd;Gujral J;Delafontaine P;Desnick RJ;Ortel TL;Billett HH;Pendleton RC;Geller NL;Halperin JL;Goldhaber SZ;Caldwell MD;Califf RM;Ellenberg JH;COAG Investigators
通讯作者：
COAG Investigators
影响因子：
64.8
作者：
Gurdasani, Deepti;Carstensen, Tommy;Tekola-Ayele, Fasil;Pagani, Luca;Tachmazidou, Ioanna;Hatzikotoulas, Konstantinos;Karthikeyan, Savita;Iles, Louise;Pollard, Martin O.;Choudhury, Ananyo;Ritchie, GrahamR. S.;Xue, Yali;Asimit, Jennifer;Nsubuga, Rebecca N.;Young, Elizabeth H.;Pomilla, Cristina;Kivinen, Katja;Rockett, Kirk;Kamali, Anatoli;Doumatey, Ayo P.;Asiki, Gershim;Seeley, Janet;Sisay-Joof, Fatoumatta;Jallow, Muminatou;Tollman, Stephen;Mekonnen, Ephrem;Ekong, Rosemary;Oljira, Tamiru;Bradman, Neil;Bojang, Kalifa;Ramsay, Michele;Adeyemo, Adebowale;Bekele, Endashaw;Motala, Ayesha;Norris, Shane A.;Pirie, Fraser;Kaleebu, Pontiano;Kwiatkowski, Dominic;Tyler-Smith, Chris;Rotimi, Charles;Zeggini, Eleftheria;Sandhu, Manjinder S.
通讯作者：
Sandhu, Manjinder S.
影响因子：
4.1
作者：
Lee, Yee Ming;Manzoor, Beenish S.;Nutescu, Edith A.
通讯作者：
Nutescu, Edith A.
影响因子：
4.5
作者：
Dong, Olivia M.;Wheeler, Stephanie B.;Wiltshire, Tim
通讯作者：
Wiltshire, Tim