Parkinson's Disease Sleep Scale-Validation of the Revised Version PDSS-2
Parkinson's Disease Sleep Scale-Validation of the Revised Version PDSS-2
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DOI：
10.1002/mds.23476
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发表时间：
2011-03-01
影响因子：
8.6
通讯作者：
Chaudhuri, Kallol Ray
中科院分区：
文献类型：
--
作者：
Trenkwalder, Claudia;Kohnen, Ralf;Chaudhuri, Kallol Ray
背景资料：帕金森病睡眠量表（Parkinson's disease sleep scale，PDSS）是一个15项的视觉模拟量表，用于评估帕金森病（Parkinson's disease，PD）患者夜间睡眠障碍的特征。目的：扩展PDSS，使其成为一个包含5个类别的频率测量量表，包括不宁腿综合征、运动不能、疼痛和睡眠呼吸暂停等未满足的需求。为了验证PDSS-2，PD患者的评级和调查人员的访谈进行了比较，从一个半结构化的访谈与照顾者/合作伙伴，并相关的量表的评级。PDSS-2在1-3天后重复测试-重测-信度。结果：总共113名PD患者显示平均（SD）总分为16.5（+/- 8.9）（范围：2-40），表明轻度至中度睡眠障碍。PDSS-2条目与总条目数的相关性较好（相关系数> 0.30）。通过因子分析，得出了三个分量表：（1）“夜间运动问题”、（2）“夜间PD症状”和（3）“睡眠障碍”。总分的α系数为0.73，子量表为0.47至0.66。总分的重测信度为0.80，各分量表的信度分别为0.69和0.77。对于区分效度，PDSS-2总分存在显著差异，这取决于CGI和Hoehn和Yahr严重程度。照顾者和病人的评级进行了比较。结论：PDSS-2具有更广泛的夜间残疾范围，更易于患者使用，是一种可靠，有效，精确和潜在的治疗响应工具，用于测量PD中的睡眠障碍。(C)2011年运动障碍协会
Background: The previous Parkinson's disease sleep scale (PDSS) is a 15-item visual analogue scale that assesses the profile of nocturnal disturbances in Parkinson's disease (PD) patients.Objective: To extend the scale so that it becomes a frequency measure scale with five categories and encompasses unmet needs such as restless legs syndrome, akinesia, pain, and sleep apnea.Methods: For validation of the PDSS-2, PD patients' ratings and investigators' interviews were compared to ratings from a semistructured interview with a caregiver/partner, and to related scales. PDSS-2 was repeated for test-retest-reliability after 1-3 days.Results: A total of 113 PD patients showed a mean (SD) total score of 16.5 (+/- 8.9) (range: 2-40) indicating mild to moderate sleep disturbances. PDSS-2 item-total correlation for proving internal consistency was satisfactory (correlations > 0.30). From a factor analysis, three subscales were derived: (1) "motor problems at night,'' (2) "PD symptoms at night'' and (3) "disturbed sleep.'' The alpha coefficient for the total score was 0.73, for subscales 0.47 to 0.66. The test-retest-reliability intra-class-coefficient for the total score was 0.80, with 0.69 and 0.77 within the subscales. For discriminative validity, significant differences were found in the PDSS-2 total score depending on CGI and Hoehn and Yahr severity levels. A comparison between caregivers' and patients' ratings was carried out. Conclusion: The PDSS-2, with an extended spectrum of nocturnal disabilities and easier use for patients, is a reliable, valid, precise, and potentially treatment-responsive tool for measuring sleep disorders in PD. (C) 2011 Movement Disorder Society