Long-term effect of persistent postpartum depression on children's psychological problems in childhood
Long-term effect of persistent postpartum depression on children's psychological problems in childhood
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DOI：
10.1016/j.jad.2022.02.061
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发表时间：
2022-03-08
影响因子：
6.6
通讯作者：
Tsuchiya, Kenji J.
中科院分区：
文献类型：
--
作者：
Tainaka, Hanae;Takahashi, Nagahide;Tsuchiya, Kenji J.
背景：母亲产后抑郁（PPD）是儿童心理问题的危险因素；然而，关于持续性PPD模式和严重程度对儿童这些问题的持续影响知之甚少。方法：数据来自滨松母婴出生队列的母亲（N = 714）和儿童（N = 768）。分别于产后2周、4周、10周和10个月采用爱丁堡产后抑郁量表对产妇抑郁进行测量。在6岁和8-9岁时分别采用优势与困难问卷对儿童的内化和外化问题进行评估。母亲们根据她们产后抑郁症的持续发展轨迹被分为4组：“无产后抑郁症”、“短暂性产后抑郁症”、“产后抑郁症加重”和“持续性产后抑郁症”。采用线性回归分析来检验PPD的持续性和严重程度与儿童内化和外化问题的关系。结果：“持续性PPD”与儿童6岁时的内化问题有显著相关性（95%CI = 2.74 [1.30-4.19], P < .001）， 8-9岁时无相关性。在任何年龄组中，均未发现PPD严重程度与儿童内化和外化问题之间的关联。局限性：“持续性PPD”和“恶化性PPD”组的样本量相对较小。母亲的抑郁状态没有与孩子的行为评估同时确定。没有关于母亲产后抑郁症治疗的信息。结论：PPD持续存在对儿童的内化问题有负向影响，但不持久。未来的研究需要确定防止儿童心理问题中PPD持续存在的保护因素。
Background: Maternal postpartum depression (PPD) is a well-established risk factor for psychological problems in children; however, little is known about the sustained impact of persistent PPD patterns and severity on these problems in children.Methods: Data were obtained from mothers (N = 714) and children (N = 768) from the Hamamatsu Birth Cohort for Mothers and Children. Maternal depression was measured using the Edinburgh Postpartum Depression Scale at 2, 4, 10 weeks and 10 months postpartum. Children's internalizing and externalizing problems were assessed using the Strengths and Difficulties Questionnaire at 6 years and 8-9 years old. Mothers were divided into 4 groups based on the trajectory of their PPD persistence: "No PPD," "Transient PPD," "Worsening PPD" and "Persistent PPD." Linear regression analysis was used to examine the association of PPD persistence and severity with children's internalizing and externalizing problems.Results: "Persistent PPD" was significantly associated with children's internalizing problems at 6 years old (Coefficient [95%CI] = 2.74 [1.30-4.19], P < .001), but no association was found at 8-9 years old. No associations were found between PPD severity and children's internalizing and externalizing problems in either age category.Limitations: "Persistent PPD" and "Worsening PPD" groups had a relatively small sample size. The mothers' depression statuses were not ascertained simultaneously with the children's behavioral assessments. There was no information regarding the mothers' treatment for PPD.Conclusion: PPD persistence negatively affected children's internalizing problems but was not long-lasting. Future studies are needed to identify protective factors against PPD persistence in children's psychological problems.