Cancer risk in the reindeer breeding Saami population of Sweden, 1961-1997
Cancer risk in the reindeer breeding Saami population of Sweden, 1961-1997
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DOI：
10.1023/a:1016232606232
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发表时间：
2001-01-01
影响因子：
13.6
通讯作者：
Kadesjö, A
中科院分区：
文献类型：
--
作者：
Hassler, S;Sjölander, P;Kadesjö, A
萨米人是斯堪的纳维亚半岛北部和科拉半岛的原住民。在一组2033只繁殖萨米人的瑞典驯鹿中，研究了1961年至1997年间患癌症的风险。总共观察到193例癌症，而在瑞典普通人群中预计有322例，在地理位置匹配的非萨米族参考人群中预计有249例。与生活在同一地区的非萨米人相比，饲养驯鹿的萨米人患前列腺癌和恶性淋巴瘤的风险在统计上显著降低，而患胃癌的风险却明显更高。虽然癌症风险随时间没有统计学上的显著变化，但时间趋势表明胃癌和前列腺癌的风险降低。研究结果表明，与同一环境下的非萨米人相比，繁殖萨米人的驯鹿患癌症的风险较低，其原因在于生活方式和/或遗传因素。
The Saami people are the natives of northern Scandinavia and the Kola Peninsula. In a cohort of 2033 Swedish reindeer breeding Saamis, the cancer risks between 1961 and 1997 were studied. In total, 193 cases of cancer were observed versus 322 expected in the general Swedish population and 249 in a geographically matched reference population of non-Saamis. In comparison to non-Saamis living in the same area, the reindeer breeding Saamis showed a statistically significant lower risk of developing cancer of the prostate and of malignant lymphoma, whereas the risk of stomach cancer was significantly higher. Although there were no statistically signi cant changes of cancer risks over time, temporal trends were indicated towards a decreased risk of cancer in the stomach and the prostate. The results suggest that the explanations of the low cancer risk of the reindeer breeding Saamis, in relation to the non-Saamis in the same environment, are to be found among lifestyle and/or genetic factors.