Superparamagnetic gadonanotubes are high-performance MRI contrast agents

Superparamagnetic gadonanotubes are high-performance MRI contrast agents
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DOI:
10.1039/b504435a
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发表时间:
2005-01-01
影响因子:
4.9
通讯作者:
Wilson, LJ
Wilson, LJ
中科院分区:
化学2区
文献类型:
--
作者:
Sitharaman, B;Kissell, KR;Wilson, LJ

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我们报道了水合Gd3+(N)离子在超短单壁碳纳米管(US管)中的纳米级负载和限制;这些Gd3+(N)@US管物种是线性超顺磁性分子磁体,其磁共振成像(MRI)效率是目前临床使用的任何基于Gd3+的造影剂(CA)的40到90倍。
We report the nanoscale loading and confinement of aquated Gd3+ (n)-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes); these Gd3+ (n)@US-tube species are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd3+-based contrast agent (CA) in current clinical use.