Risk of onset of second neoplasms and successive neoplasms in patients with a head and neck index tumour
Risk of onset of second neoplasms and successive neoplasms in patients with a head and neck index tumour
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DOI：
10.1016/j.otorri.2018.11.003
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发表时间：
2020-01-01
影响因子：
1
通讯作者：
Quer, Miquel
中科院分区：
文献类型：
--
作者：
Leon, Xavier;Garcia, Jacinto;Quer, Miquel
目的：分析头颈部鳞状细胞癌patients.Material and methods队列中第二次和连续肿瘤出现的发生率：我们对1985-2016年期间诊断的4，458例头颈部索引肿瘤患者进行了回顾性研究。我们评估了第二个肿瘤和连续肿瘤的发生率在一段时间的30 years.Results：在随访期间，1,203例（27.0%）有第二个肿瘤，242例（5.4%）的第三个肿瘤，58例（1.3%）的第四个肿瘤，和8例（0.2%）5个或更多的连续肿瘤。第二肿瘤的发生率为每年3.5%，在整个随访期间保持相对稳定。第二个肿瘤的患者出现第三个肿瘤的风险较高，第三个肿瘤的患者出现第四个肿瘤的风险较高。百分之七十八的第二肿瘤，88%的第三肿瘤，和89.6%的第四肿瘤出现在流行病学上与烟草和酒精use.Conclusions相关的位置：第二肿瘤后，头部和颈部指数肿瘤出现在一个恒定的速度为3.5%，每年在整个随访期间。(C)2019 Sociedad Espanola de Otorrinolaringologia y Cirugia de Cabeza y Cuello.由Elsevier Espana出版，S.L.U. All rights reserved.
Objective: To analyse the incidence of appearance of second and successive neoplasms in a cohort of head and neck squamous carcinoma patients.Material and methods: We conducted a retrospective study with 4,458 patients with an index tumour located in the head and neck diagnosed during the 1985-2016 period. We evaluated the incidence of appearance of second neoplasms and successive neoplasms over a period of 30 years.Results: During the follow-up, 1,203 patients (27.0%) had a second neoplasm, 242 patients (5.4%) a third neoplasm, 58 patients (1.3%) a fourth neoplasm, and 8 patients (0.2%) 5 or more successive neoplasms. The incidence of appearance of second neoplasms was 3.5% per year, remaining relatively constant throughout the follow-up period. The patients with a second neoplasm had a higher risk of appearance of a third neoplasm, and those with a third neoplasm had a higher risk of a fourth. Seventy-eight percent of the second neoplasms, 88% of the third neoplasms, and 89.6% of the fourth neoplasms appeared in locations epidemiologically related to tobacco and alcohol use.Conclusions: Second neoplasms after a head and neck index tumour appeared at a constant rate of 3.5% per year throughout the entire follow-up period. (C) 2019 Sociedad Espanola de Otorrinolaringologia y Cirugia de Cabeza y Cuello. Published by Elsevier Espana, S.L.U. All rights reserved.