Escherichia coli DNA repair genes radA and sms are the same gene.
Escherichia coli DNA repair genes radA and sms are the same gene.
复制标题
大肠杆菌DNA修复基因radA和sms是同一个基因。
DOI：
10.1128/jb.178.16.5045-5048.1996
复制
发表时间：
1996
影响因子：
3.2
通讯作者：
Sargentini,NJ
中科院分区：
文献类型：
--
作者：
Song,Y;Sargentini,NJ
携带 radA100 或 sms 突变的大肠杆菌菌株对甲磺酸甲酯或紫外线辐射处理的敏感性以及紫外线辐射存活的质粒互补模式是相同的。对 radA 突变体和 radA+ 菌株的 DNA 测序分析以及将其序列与已发表的 sms 基因序列进行比较表明，radA 突变体仅存在 G 到 A 的过渡突变，预计该突变会将锌指基序中的半胱氨酸变为酪氨酸。 sms 基因被推断与先前描述的 radA 基因相同。
Escherichia coli strains carrying radA100 or sms mutations were identical in their sensitivities to either methyl methanesulfonate or UV radiation treatment and in their plasmid complementation patterns for UV radiation survival. DNA sequencing analysis of the radA mutant and radA+ strains and comparison of their sequences with the published sms gene sequence showed the radA mutant to differ only by a G-to-A transition mutation, which is predicted to change a cysteine in a zinc-finger motif to tyrosine. The sms gene is concluded to be identical to the previously described radA gene.