Percutaneous Microwave Ablation of Liver Cancer Adjacent to the Gastrointestinal Tract
Percutaneous Microwave Ablation of Liver Cancer Adjacent to the Gastrointestinal Tract
复制标题
DOI：
10.1007/s11605-008-0710-9
复制
发表时间：
2009-02-01
影响因子：
3.2
通讯作者：
Dong, Baowei
中科院分区：
文献类型：
--
作者：
Zhou, Pei;Liang, Ping;Dong, Baowei
本研究旨在前瞻性评价温度监测辅助下经皮微波消融乙醇注射治疗邻接胃肠道的肝癌的安全性和有效性。纳入179例接受经皮微波消融治疗的肝肿瘤。距胃肠道小于5mm的病灶53例为胃肠组。距肝表面及肝血管第一、二支以上病灶126个为对照组。对于胃肠组肿瘤，监测并控制胃肠道近端边缘消融组织温度在45°C至58°C之间波动10 min以上。将乙醇（2-27ml）注射到胃肠道组53个病灶中的33个的边缘组织中。胃肠组53个肿瘤中的47个（88.7%）和对照组126个肿瘤中的116个（92.1%）实现完全消融（p>0.05）。两组均未出现立即并发症和围手术期并发症。肿瘤种植发生在胃肠道组的 1 个和对照组的 2 个中。无胆管损伤迟发性并发症。在严格的体温监测下，乙醇注射辅助微波消融对于胃肠道邻近的肝脏肿瘤安全性高，且完全消融率高。
The purpose of the study was to prospectively evaluate safety and effectiveness of percutaneous microwave ablation under temperature monitoring assisted with ethanol injection for liver cancer abutting gastrointestinal tract.One hundred seventy-nine hepatic tumors that underwent percutaneous microwave ablation with curative intention were included. Fifty-three lesions located less than 5 mm from gastrointestinal tract were in gastrointestinal group. One hundred twenty-six lesions located more than 5 mm from hepatic surface and first or second branch of hepatic vessels were in control group. The temperature of marginal ablation tissue proximal to gastrointestinal tract was monitored and controlled to fluctuating between 45A degrees C and 58A degrees C for more than 10 min for tumors in the gastrointestinal group. Ethanol (2-27 ml) was injected into marginal tissue in 33 of 53 lesions of the GI group.Forty-seven of 53 tumors (88.7%) in the gastrointestinal group and 116 of 126 tumors (92.1%) in the control group achieved complete ablation (p > 0.05). There were neither immediate nor periprocedural complications in both groups. Tumor seeding happened in one of the gastrointestinal group and two of the control group. There was no delayed complication of bile ducts injury.Under strict temperature monitoring, microwave ablation assisted with ethanol injection is safe and achieves a high complete ablation rate for hepatic tumors adjacent to gastrointestinal tract.