Thiosialoside clusters using carbosilane dendrimer core scaffolds as a new class of influenza neuraminidase inhibitors
Thiosialoside clusters using carbosilane dendrimer core scaffolds as a new class of influenza neuraminidase inhibitors
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DOI：
10.1016/j.bmcl.2006.10.085
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发表时间：
2007-02-01
影响因子：
2.7
通讯作者：
Matsuoka, Koji
中科院分区：
文献类型：
--
作者：
Sakamoto, Jun-Ichi;Koyama, Tetsuo;Matsuoka, Koji
An efficient synthesis of a series of carbosilane dendrimers uniformly functionalized with alpha-thioglycoside of sialic acid was accomplished. The results of a preliminary study on biological responses against influenza virus sialidases using thiosialoside clusters showed that some of the glycodendrimers have inhibitory potencies against the sialidases. (c) 2006 Elsevier Ltd. All rights reserved.
