The Mx GTPase family of interferon-induced antiviral proteins
The Mx GTPase family of interferon-induced antiviral proteins
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DOI：
10.1016/j.micinf.2007.09.010
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发表时间：
2007-11-01
影响因子：
5.8
通讯作者：
Kochs, Georg
中科院分区：
文献类型：
--
作者：
Haller, Otto;Stertz, Silke;Kochs, Georg
Mx 蛋白是干扰素诱导的大 GTP 酶动力超家族的成员。它们通过阻断复制周期的早期阶段来抑制多种病毒。对基因定义的小鼠品系的研究强调了它们在早期抗病毒宿主防御中的强大作用。 (c) 2007 年 Elsevier Masson SAS。版权所有。
Mx proteins are interferon-induced members of the dynamin superfamily of large GTPases. They inhibit a wide range of viruses by blocking an early stage of the replication cycle. Studies in genetically defined mouse strains highlight their powerful action in early antiviral host defence. (c) 2007 Elsevier Masson SAS. All rights reserved.