How common is white coat hypertension?
How common is white coat hypertension?
复制标题
DOI：
10.1001/jama.1988.03720020027031
复制
发表时间：
1988-01
期刊：
影响因子：
--
通讯作者：
T. Pickering;G. James;Charlene Boddie;G. Harshfield;S. Blank;J. Laragh
中科院分区：
文献类型：
--
作者：
T. Pickering;G. James;Charlene Boddie;G. Harshfield;S. Blank;J. Laragh
在292例未经治疗的临界高血压患者（门诊舒张压持续在90 - 104 mm Hg之间）中，发现21%的患者具有正常的日间动态血压（从血压正常的受试者人群中定义）。这些患者被定义为患有“白色大衣”高血压，与在门诊和动态监测期间血压升高的患者相比，他们更可能是女性和年轻人，体重更轻，最近被诊断出来。患有白色被毛高血压的患者在工作时没有表现出血压不稳定性的普遍增加，也没有表现出过度的升压反应。这种现象在由医生测量血压时比由技术人员测量血压时更明显。在这类患者中，升压反应可能相对特异于医生的办公室，并导致高血压的严重错误分类。
Twenty-one percent of 292 patients with untreated borderline hypertension (clinic diastolic blood pressures persistently between 90 and 104 mm Hg) were found to have normal daytime ambulatory pressures (defined from a population of normotensive subjects). These patients were defined as having "white coat" hypertension, and they were more likely to be female and younger, to weigh less, and to be more recently diagnosed than patients whose pressure was elevated both in the clinic and during ambulatory monitoring. Patients with white coat hypertension did not show a generalized increase of blood pressure lability, nor an exaggerated pressor response while at work. The phenomenon is more pronounced when blood pressure is measured by a physician than by a technician. In such patients, the pressor response may be relatively specific to the physician's office and lead to significant misclassification of hypertension.