Single Session of Transcranial Direct Current Stimulation Transiently Increases Knee Extensor Force in Patients With Hemiparetic Stroke
Single Session of Transcranial Direct Current Stimulation Transiently Increases Knee Extensor Force in Patients With Hemiparetic Stroke
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DOI：
10.1177/1545968311402091
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发表时间：
2011-07-01
影响因子：
4.2
通讯作者：
Watanabe, Katsumi
中科院分区：
文献类型：
--
作者：
Tanaka, Satoshi;Takeda, Kotaro;Watanabe, Katsumi
背景运动皮层的经颅直流电刺激（tDCS）可以增强中风后瘫痪上肢的表现。报告的对下肢（LL）功能的影响很少。Objective.作者检查了tDCS是否可以增加麻痹性四头肌的力量产生。方法.在该双盲、交叉、假对照实验设计中，8名慢性皮质下卒中受试者在受累半球LL运动皮质代表的阳极或假tDCS之前、期间和之后使用其偏瘫腿进行膝关节伸展。还记录了受影响的握力。结果与基线和假刺激相比，阳极tDCS期间的最大膝关节伸展力增加了21 N（13.2%，P <0.01）。增加持续不到30分钟。最大握力没有变化。结论.阳极tDCS短暂增强膝关节伸肌力量。当地雇员人数的增加幅度不大。因此，tDCS可能会增加脑卒中患者的康复时，结合下肢强化或功能训练。
Background. Transcranial direct current stimulation (tDCS) of the motor cortex can enhance the performance of a paretic upper extremity after stroke. Reported effects on lower limb (LL) function are sparse. Objective. The authors examined whether tDCS can increase the force production of the paretic quadriceps. Methods. In this double-blind, crossover, sham-controlled experimental design, 8 participants with chronic subcortical stroke performed knee extension using their hemiparetic leg before, during, and after anodal or sham tDCS of the LL motor cortex representation in the affected hemisphere. Affected hand-grip force was also recorded. Results. The maximal knee-extension force increased by 21 N (13.2%, P < .01) during anodal tDCS compared with baseline and sham stimulation. The increase persisted less than 30 minutes. Maximal hand-grip force did not change. Conclusions. Anodal tDCS transiently enhanced knee extensor strength. The modest increase was specific to the LL. Thus, tDCS might augment the rehabilitation of stroke patients when combined with lower extremity strengthening or functional training.