EFFECT OF DOPA ON SPINAL CORD .6. HALF-CENTRE ORGANIZATION OF INTERNEURONES TRANSMITTING EFFECTS FROM FLEXOR REFLEX AFFERENTS
EFFECT OF DOPA ON SPINAL CORD .6. HALF-CENTRE ORGANIZATION OF INTERNEURONES TRANSMITTING EFFECTS FROM FLEXOR REFLEX AFFERENTS
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DOI：
10.1111/j.1748-1716.1967.tb03637.x
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发表时间：
1967-01-01
期刊：
影响因子：
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通讯作者：
LUNDBERG, A
中科院分区：
文献类型：
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作者：
JANKOWSKA, E;JUKES, MGM;LUNDBERG, A
在未麻醉的脊髓猫中，在腰骶脊髓中进行了系统的微电极探索，以寻找可能传递静脉注射多巴后FRA（屈肌反射传入）中的齐射引起的晚期持久反射效应的中间神经元。可能传递这些迟发效应的中间神经元被发现在Rexed's层VII的外侧部分，并且鉴定出三种主要类型：A）从同侧FRA激活并且从对侧FRA抑制的细胞，B）从对侧FRA激活并且从同侧FRA抑制的细胞，C）从同侧和对侧FRA激活的细胞。接受野和其他标准表明，A型和B型分别将兴奋作用传递到屈肌和伸肌运动神经元，C型去极化传递到la传入终末。这些途径的功能组织主要讨论有关的机制负责长潜伏期和持续时间的放电。
In unanesthetized spinal cats a systematic microelectrode exploration was made in the lumbosacral spinal cord in order to find interneurons that may transmit the late longlasting reflex effects that volleys in the FRA (flexor reflex afferents) evoke after an intravenous injection of DOPA. Interneurons that may transmit these late effects are found in the lateral part of Rexed''s layer VII and three main types are identified: A) cells activated from the ipsilateral FRA and inhibited from the contralateral FRA, B) cells activiated from the contralateral FRA and inhibited from the ipsilateral FRA, C) cells activated from both the ipsilateral and contralateral FRA. The receptive fields and other criteria employed suggest that type A and B transmit excitatory action to flexor and extensor motoneurons respectively, and type C depolarization to la afferent terminals. The functional organization of these pathways is discussed mainly in relation to the mechanisms responsible for the long latency and duration of the discharge.