A stereological analysis of the lateral geniculate nucleus in adult Macaca nemestrina monkeys
A stereological analysis of the lateral geniculate nucleus in adult Macaca nemestrina monkeys
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DOI：
10.1017/s0952523899165131
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发表时间：
1999-09-01
影响因子：
1.9
通讯作者：
Cavada, C
中科院分区：
文献类型：
--
作者：
Blasco, B;Avenda単o, C;Cavada, C
用Cavalieri法和光学分割仪对7只成年恒河猴(Macaca Nomestrina)背外侧膝状体核(DLGN)的体积和神经元数量进行了测定。有选择地获得了对细胞核的小细胞(P)、大细胞(M)和板层加浅层(I+S)的无偏估计。DLGN的平均体积为56.5 mm(3)，平均含有179万个神经元。P层贡献%的体积和dLGN 83%的神经元，其他层的相应比例分别为13%和9%(M)和23%和8%(I+S)。神经元数量的个体间变异性很大，在两倍的范围内变化，而体积估计的变异性较低。由于目前还没有关于尾辫dLGN的公开数据，因此将本研究结果与其他猕猴物种dLGN的定量研究进行了比较，特别强调了所使用的方法的讨论。
The Cavalieri method and the optical fractionator were employed to estimate the volume and neuron numbers, respectively, of the dorsal lateral geniculate nucleus (dLGN) in seven adult malt pigtail monkeys (Macaca nemestrina). Unbiased estimates were selectively obtained for the parvocellular (P), magnocellular (M), and interlaminar plus superficial (I + S) layers of the nucleus. The dLGN had a mean volume of 56.5 mm(3), and contained on average 1.79 million neurons. The P layers contributed 64% of the volume and 83% of the neurons in the dLGN; the corresponding proportions for the other layers were 13% and 9% (M), and 23% and 8% (I + S). Interindividual variability was large for neuron counts, which varied within a two-fold range, and lower for volume estimates. Since no published data are available for the pigtail dLGN, the present results are compared with quantitative studies of the dLGN in other macaque species, placing special emphasis in the discussion of the methodologies used.