Vitamin C supplementation does not alter the immune response to 2.5 hours of running.
Vitamin C supplementation does not alter the immune response to 2.5 hours of running.
复制标题
补充维生素 C 不会改变 2.5 小时跑步的免疫反应。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
S. Nehlsen
中科院分区：
文献类型：
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作者：
D. Nieman;D. Henson;D. Butterworth;B. Warren;J. Davis;O. Fagoaga;S. Nehlsen
这项随机、双盲、安慰剂对照研究旨在确定维生素C补充剂对2.5小时高强度跑步免疫反应的影响。12名有经验的马拉松运动员（最大摄氧量51.6 +/- 1.5 ml.kg-1.min-1，年龄40.5 +/- 2.0岁）被随机分为维生素C组（1，000 mg/天，持续8天）或安慰剂组。在测试当天，受试者以75- 80%VO2最大值跑步2.5小时，在之前和之后6小时采集5份血样。分析血液样本的皮质醇和儿茶酚胺;白细胞亚群;白细胞介素-6;自然杀伤细胞活性;伴刀豆球蛋白A、植物血凝素和美洲商陆有丝分裂原诱导的淋巴细胞增殖;粒细胞吞噬作用和活化氧化爆发。与安慰剂相比，维生素C补充剂对2.5小时高强度跑步后这些激素或免疫指标的变化模式没有显著影响。
This randomized, double-blind, placebo-controlled study was designed to determine the influence of vitamin C supplementation on the immune response to 2.5 hr of high-intensity running. Twelve experienced marathon runners (VO2 max 51.6 +/- 1.5 ml.kg-1.min-1, age 40.5 +/- 2.0 years) were randomized into vitamin C (1,000 mg/day for 8 days) or placebo groups. On the test day, subjects ran at 75-80% VO2 max for 2.5 hr, with five blood samples taken before and for 6 hr after. Blood samples were analyzed for cortisol and catecholamines; leukocyte subsets; interleukin-6; natural killer cell activity; lymphocyte proliferation as induced by concanavalin A, phytohemagglutinin, and pokeweed mitogen; and granulocyte phagocytosis and activated oxidative burst. Compared with placebo, vitamin C supplementation had no significant effect on the pattern of change in any of these hormonal or immune measures following 2.5 hr of intensive running.
边缘抗坏血酸缺乏对豚鼠唾液皮质醇水平的影响。
影响因子：
3
作者：
Enwonwu,CO;Sawiris,P;Chanaud,N
通讯作者：
Chanaud,N