Enhanced cognitive behaviour therapy for adults with anorexia nervosa: a UK-Italy study.
Enhanced cognitive behaviour therapy for adults with anorexia nervosa: a UK-Italy study.
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DOI：
10.1016/j.brat.2012.09.010
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发表时间：
2013-01
影响因子：
4.1
通讯作者：
Dalle Grave, Riccardo
中科院分区：
文献类型：
--
作者：
Fairburn, Christopher G.;Cooper, Zafra;Doll, Helen A.;O'Connor, Marianne E.;Palmer, Robert L.;Dalle Grave, Riccardo
神经性厌食症很难治疗，没有强有力的证据支持任何治疗。由于这种情况并不常见，因此建议新的治疗方法在随机对照试验中进行评估之前应进行广泛的初步测试。本研究的目的是建立“增强”认知行为疗法（CBT-E）后的即时和长期结果。从英国和意大利的连续转诊诊所招募了99例明显神经性厌食症（体重指数≤ 17.5）的成人患者。每个人在40周内接受40次CBT-E治疗，没有同时治疗。64%的患者能够完成门诊治疗，这些患者的体重（7.47 kg，SD 4.93）和BMI（2.77，SD 1.81）显著增加。饮食失调的特征也明显改善。在60周的随访期内，尽管进行了最小限度的额外治疗，但几乎没有恶化。这些发现为CBT-E的使用提供了强有力的初步支持，并证明其在随机对照试验中的进一步评价是合理的。由于CBT-E已经被确定为神经性贪食症和饮食失调症的治疗方法，研究结果也证实了CBT-E在其范围内具有跨诊断性。CBT-E旨在解决饮食失调的精神病理学问题。结果表明CBT-E可用于明显的神经性厌食症患者。三分之二的患者完成了治疗。在完成者中，有一个实质性的，保持良好的反应。研究结果证实，CBT-E在其范围内是transdiagnosis。
Anorexia nervosa is difficult to treat and no treatment is supported by robust evidence. As it is uncommon, it has been recommended that new treatments should undergo extensive preliminary testing before being evaluated in randomized controlled trials. The aim of the present study was to establish the immediate and longer-term outcome following “enhanced” cognitive behaviour therapy (CBT-E). Ninety-nine adult patients with marked anorexia nervosa (body mass index ≤ 17.5) were recruited from consecutive referrals to clinics in the UK and Italy. Each was offered 40 sessions of CBT-E over 40 weeks with no concurrent treatment. Sixty-four percent of the patients were able to complete this outpatient treatment and in these patients there was a substantial increase in weight (7.47 kg, SD 4.93) and BMI (2.77, SD 1.81). Eating disorder features also improved markedly. Over the 60-week follow-up period there was little deterioration despite minimal additional treatment. These findings provide strong preliminary support for this use of CBT-E and justify its further evaluation in randomized controlled trials. As CBT-E has already been established as a treatment for bulimia nervosa and eating disorder not otherwise specified, the findings also confirm that CBT-E is transdiagnostic in its scope. ► CBT-E is designed to address eating disorder psychopathology. ► The findings show that CBT-E can be used with patients with marked anorexia nervosa. ► Two-thirds of the patients completed treatment. ► Among the completers there was a substantial, and well maintained, response. ► The findings confirm that CBT-E is transdiagnostic in its scope.
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影响因子：
17.7
作者：
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通讯作者：
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