Neonatal Drug Withdrawal
Neonatal Drug Withdrawal
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DOI：
10.1542/peds.2011-3212
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发表时间：
2012-02-01
期刊：
影响因子：
8
通讯作者：
Tan, Rosemarie C.
中科院分区：
文献类型：
--
作者：
Hudak, Mark L.;Tan, Rosemarie C.
母亲在怀孕期间使用某些药物可能会导致与戒断或急性毒性一致的短暂新生儿症状，或导致与持久药物作用一致的持续症状。此外，接受阿片类药物或苯二氮卓类药物镇痛或镇静治疗的住院婴儿可能有出现戒断症状的风险。该声明更新了有关暴露于宫内药物的婴儿的临床表现和戒断治疗选择的信息，并扩展到包括需要停止使用镇痛药或镇静剂的住院婴儿的循证管理方法。儿科 2012；129：e540-e560
Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity or cause sustained signs consistent with a lasting drug effect. In addition, hospitalized infants who are treated with opioids or benzodiazepines to provide analgesia or sedation may be at risk for manifesting signs of withdrawal. This statement updates information about the clinical presentation of infants exposed to intrauterine drugs and the therapeutic options for treatment of withdrawal and is expanded to include evidence-based approaches to the management of the hospitalized infant who requires weaning from analgesics or sedatives. Pediatrics 2012;129:e540-e560